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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Ginsenoside Rh2, Sodium selenite
Phytochemical Name Ginsenoside Rh2 (PubChem CID: 119307 )
Anticancer drug Name Sodium selenite (PubChem CID: 24934 )
Structure of
Phytochemical		 2D-img
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2D MOL 3D MOL
Structure of
Anticancer Drug		 2D-img
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 685
Ref_1
Pair Name Ginsenoside Rh2, Sodium selenite
Disease Info [ICD-11: 2B91.Z] Colorectal cancer Investigative
Biological Phenomena Induction-->Blockade of cell cycle in G1/S phase
Gene Regulation Up-regulation Expression BAX hsa581
Down-regulation Expression BCL2 hsa596
Up-regulation Expression CASP3 hsa836
In Vitro Model HCT 116 Colon carcinoma Homo sapiens (Human) CVCL_0291
Result Sodium selenite and G-Rh2 combination have a synergistic effect on cell growth inhibition (57%) compared with sodium selenite (25%) and G-Rh2 alone (28%) after 24 hours of treatment
03. Reference
No. Title Href
1 Combined Effect of Sodium Selenite and Ginsenoside Rh2 on HCT116 Human Colorectal Carcinoma Cells. Arch Iran Med. 2016 Jan;19(1):23-9. Click
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